4-(叔丁氧基羰基氨基)苯甲酸乙酯合成路线 （共 6 条）
参考文献
Frank, Kristine E.; Aube, Jeffrey
Journal of Organic Chemistry, 2000 , vol. 65, # 3 p. 655 - 666
反应条件
cBRIDP; bis(η3-allyl-μ-chloropalladium(II)); sodium t-butanolate in water T=50°C; 24 h; Inert atmosphereGreen chemistry;
参考文献
Isley, Nicholas A.; Dobarco, Sebastian; Lipshutz, Bruce H.
Green Chemistry, 2014 , vol. 16, # 3 p. 1480 - 1488
反应条件
n,n,n'-triethylethylenediamine in acetonitrile 2 h; Yield given;
参考文献
Grehn, Leif; Gunnarsson, Kerstin; Ragnarsson, Ulf
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 1 p. 18 - 23
反应条件
1: 4-dimethylaminopyridine / acetonitrile / 1.) reflux, 2.) room temperature, 2 h 2: 2-diethylaminodiethylamine / acetonitrile / 2 h View Scheme
参考文献
Grehn, Leif; Gunnarsson, Kerstin; Ragnarsson, Ulf
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 1 p. 18 - 23
反应条件
1: 4-dimethylaminopyridine / acetonitrile / 1.) reflux, 2.) room temperature, 2 h 2: 2-diethylaminodiethylamine / acetonitrile / 2 h View Scheme
参考文献
Grehn, Leif; Gunnarsson, Kerstin; Ragnarsson, Ulf
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 1 p. 18 - 23
反应条件
1: With lithium hydroxide; water in tetrahydrofuran; methanol T=20°C; 16 h; 2: With hydrogenchloride in water
参考文献
Eli Lilly and Company
Patent: US6639107 B1, 2003 ;
Location in patent: Page/Page column 36 ;
