反应条件
1: NBS / tetrahydrofuran; H2O / 1.) 30 min, 0 deg C; 2.) 1 h, RT 2: K2CO3 / methanol / 2 h / Ambient temperature 3: 19.2 g / HIO4*2H2O / diethyl ether / 0.17 h 4: 45 percent / HCl, NaBH3CN / tetrahydrofuran / 0.5 h / Ambient temperature; pH 3 5: 92 percent / 30percent H2O2 / methanol / 12 h / Ambient temperature View Scheme
参考文献
Ceruti, Maurizio; Balliano, Gianni; Viola, Franca; Cattel, Luigi; Gerst, Nicolas; Schuber, Francis
European Journal of Medicinal Chemistry, 1987 , vol. 22, p. 199 - 208
