反应条件
Multi-step reaction with 7 steps 1: 1.) n-BuLi, 2.) HMPA / 1.) THF, hexane, -78 deg C, 10 min, 2.) THF, hexane, a) from -78 deg C to RT, 2 h, b) RT, 16 h2: pyridinium p-toluenesulfonate / methanol / 18 h3: 92 percent / CBr4, n-Bu3P / diethyl ether / 0.25 h / 0 °C4: 31 percent / Na2S*9H2O / ethanol; H2O / 25 °C5: 68 percent / m-chloroperbenzoic acid / CH2Cl2 / 0.5 h / -30 °C6: pyridine, SO2Cl2 / CH2Cl2 / 0.67 h / -78 °C7: m-chloroperbenzoic acid / CH2Cl2 / 16 h / Ambient temperature
参考文献
Nicolaou; Zuccarello; Riemer; Estevez; Dai Journal of the American Chemical Society, 1992 , vol. 114, # 19 p. 7360 - 7371
