Richards, Elinor L; Murphy, Patrick J; Dinon, Francesca; Fratucello, Silvia; Brown, Paul M; Gelbrich, Thomas; Hursthouse, Michael B
Tetrahedron, 2001 , vol. 57, # 36 p. 7771 - 7784
1: (2R)-2-hydroxy-2-phenylethylamine; glutardialdehyde With citric acid in water
T=0°C; 0.5 h;
2: potassium cyanide in dichloromethane; water
T=0 - 20°C; 3.5 h;
3: With sodium hydroxide; zinc dibromide
more than 3 stages;
参考文献
GLAXO GROUP LIMITED
Patent: WO2009/34133 A1, 2009 ;
Location in patent: Page/Page column 12-13 ;
WO 2009/034133 A1
