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1: With 1,1'-bis-(diphenylphosphino)ferrocene; potassium carbonate; palladium diacetate in DMF (N,N-dimethyl-formamide); water
T=100°C; 18 h;
2: With hydrogenchloride; water in DMF (N,N-dimethyl-formamide); water
T=20°C;
参考文献
CYTOKINETICS, INC.
Patent: WO2005/5382 A2, 2005 ;
Location in patent: Page 55 ;
