4-(4-氯苯基)-1H-吡唑合成路线 （共 3 条）
反应条件
1: trichlorophosphate; sodium perchlorate monohydrate / 5 - 95 °C
2: sodium hydroxide / water / 0.25 h / 90 °C
3: hydrazine / 20 °C
View Scheme
参考文献
Li, Shenghui; Xu, Shengjie; Tang, Yonghe; Ding, Shan; Zhang, Jinchao; Wang, Shuxiang; Zhou, Guoqiang; Zhou, Chuanqi; Li, Xiaoliu
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 2 p. 586 - 590
反应条件
1: CHCl3 / 72 h / Ambient temperature
2: BF3*Et2O / 0.25 h / Heating
3: 10percent KOH / methanol / 0.5 h / 65 °C
4: ethane-1,2-diol / 2 h / 200 °C
View Scheme
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
反应条件
1: 10percent KOH / methanol / 0.5 h / 65 °C
2: ethane-1,2-diol / 2 h / 200 °C
View Scheme
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
