3-氨基噻吩并[3,2-b]吡啶-2-甲酸甲酯合成路线 (共 6 条)
反应条件
potassium carbonate in chloroform; water; N,N-dimethyl-formamide
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;
反应条件
potassium hydroxide in water; N,N-dimethyl-formamide T=0°C;
参考文献
Calhelha, Ricardo C.; Queiroz, Maria-Joao R.P.
Tetrahedron Letters, 2010 , vol. 51, # 2 p. 281 - 283
反应条件
1: triethylamine / acetonitrile / 20 h / Reflux 2: potassium carbonate / acetonitrile / 3 h / Reflux View Scheme
反应条件
1: dihydrogen peroxide / water; acetic acid / 20 h / 80 °C 2: triethylamine / acetonitrile / 20 h / Reflux 3: potassium carbonate / acetonitrile / 3 h / Reflux View Scheme
反应条件
1: hypophosphorous ether; sodium nitrite / water / 3 h / Cooling with ice bath
2: lithium aluminium tetrahydride / tetrahydrofuran / 0.83 h / 0 °C
View Scheme
参考文献
SU, Wei-Guo; JIA, Hong; DAI, Guangxiu
Patent: US2012/245178 A1, 2012 ;
US 20120245178 A1
反应条件
sodium hydroxide; sodium nitrite in water; hypophosphorous ether
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;