Fmoc-O-三苯甲基-L-丝氨酸合成路线 (共 4 条)
反应条件
sodium carbonate in 1,4-dioxane 1.) 1h, 0 deg C, 2.) 12h, room temperature;
参考文献
Barlos, Kleomenis; Mamos, Petros; Papaioannou, Dionysios; Patrianakou, Stella; Sanida, Chariklia; Schaefer, Wolfram
Liebigs Annalen der Chemie, 1987 , p. 1025 - 1030
反应条件
1: With diethylamine in dichloromethane 3 h; 2: With sodium hydroxide; water
参考文献
M. Martin, Lenore; Hu, Bi-Huang
Patent: US2006/161007 A1, 2006 ;
Location in patent: Page/Page column 10; Sheet 3 ;
参考文献
Biron, Eric; Chatterjee, Jayanta; Kessler, Horst
Organic Letters, 2006 , vol. 8, # 11 p. 2417 - 2420
反应条件
1: 78 percent / CH2Cl2; tetrahydrofuran / 20 °C
2: 99 percent / trifluoroacetic acid; triisopropylsilane / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Rothman, Deborah M.; Vazquez, M. Eugenio; Vogel, Elizabeth M.; Imperiali, Barbara
Journal of Organic Chemistry, 2003 , vol. 68, # 17 p. 6795 - 6798