(2-羟基甲基苯氧基)-乙酸乙酯合成路线 （共 6 条）
反应条件
sodium tetrahydroborate; sodium ethanolate in ethanol 1.) 0-5 deg C; 2.) below 8 deg C, 3.75 h;
参考文献
Edwards; Readhead; Tweddle
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 495 - 496
反应条件
1: 82 percent / K2CO3, KI / dimethylformamide / 20 h / Ambient temperature 2: 100 percent / 1.) C2H5ONa; 2.) NaBH4 / ethanol / 1.) 0-5 deg C; 2.) below 8 deg C, 3.75 h View Scheme
参考文献
Ashram, Muhammad
Journal of the Chemical Society, Perkin Transactions 2, 2002 , # 10 p. 1662 - 1668
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Hidaka, Koushi; Kimura, Tooru; Ruben, Adam J.; Uemura, Tsuyoshi; Kamiya, Mami; Kiso, Aiko; Okamoto, Tetsuya; Tsuchiya, Yumi; Hayashi, Yoshio; Freire, Ernesto; Kiso, Yoshiaki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10049 - 10060
反应条件
1: 78 percent / SOCl2, pyridine / CH2Cl2 / 1.5 h / Heating 2: NaH / various solvent(s); paraffin / 16 h / Ambient temperature 3: 2N aq.NaOH / 2 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, # 2 p. 495 - 496
反应条件
sodium hydroxide; water in methanol
参考文献
Hidaka, Koushi; Kimura, Tooru; Ruben, Adam J.; Uemura, Tsuyoshi; Kamiya, Mami; Kiso, Aiko; Okamoto, Tetsuya; Tsuchiya, Yumi; Hayashi, Yoshio; Freire, Ernesto; Kiso, Yoshiaki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 23 p. 10049 - 10060
反应条件
1: 78 percent / SOCl2, pyridine / CH2Cl2 / 1.5 h / Heating
2: NaH / various solvent(s); paraffin / 16 h / Ambient temperature
View Scheme
参考文献
Edwards; Readhead; Tweddle
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 495 - 496
