苯并[d][1,3]二氧代-4-氨基甲酸叔丁酯合成路线 （共 6 条）
反应条件
diphenyl-phosphinic acid; triethylamine in 1,4-dioxane 5 h; Heating;
参考文献
Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard
Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887
反应条件
1: 73 percent / KOH / methanol; H2O / 2 h / 20 °C 2: 77 percent / DPPA; Et3N / dioxane / 5 h / Heating View Scheme
参考文献
Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard
Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887
反应条件
1.1: 40 percent / H2SO4 / 24 h / 60 °C 2.1: KF / dimethylformamide / 0.5 h / 20 °C 2.2: 80 percent / dimethylformamide / 3 h / 120 °C 3.1: 73 percent / KOH / methanol; H2O / 2 h / 20 °C 4.1: 77 percent / DPPA; Et3N / dioxane / 5 h / Heating View Scheme
参考文献
Ple, Patrick A.; Green, Tim P.; Hennequin, Laurent F.; Curwen, Jon; Fennell, Michael; Allen, Jack; Lambert-Van Der Brempt, Christine; Costello, Gerard
Journal of Medicinal Chemistry, 2004 , vol. 47, # 4 p. 871 - 887
反应条件
diphenylphosphoranyl azide; triethylamine in 1,4-dioxane 8 h; Heating;
参考文献
Neville, Charles F.; Grundon, Michael F.; Ramachandran, Venkat N.; Reisch, Johannes
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 2 p. 259 - 262
反应条件
diphenylphosphoranyl azide; triethylamine in 1,4-dioxane; tert-butyl alcohol 8 h; Heating;
参考文献
Neville, Charles F.; Grundon, Michael F.; Ramachandran, Venkat N.; Reisch, Johannes
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 2 p. 259 - 262
反应条件
hydrogenchloride in 1,4-dioxane T=18 - 22°C; 1 h;
参考文献
WO2004/103996 A1, ;
Page 50 ;
WO 2004/103996 A1
