8-氟-2,3-二氢苯并吡喃-4-酮合成路线 （共 3 条）
反应条件
1: With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane 2: With AlCl3, aluminium chloride in dichloromethane
参考文献
US2008/119496 A1, ;
Page/Page column 12; 30 ;
反应条件
1: With thionyl chloride in toluene 17 h; Heating / reflux; 2: With trifluorormethanesulfonic acid in chloroform T=-65 - 20°C;
参考文献
WO2008/151927 A2, ;
Page/Page column 62 ;
反应条件
1: 59 percent 2: 86 percent View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 31, # 1 p. 230 - 243
