3-氯-5H-吡咯并[2,3-b]吡嗪合成路线 （共 2 条）
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 3 h; Reflux;
参考文献
de Vicente Fidalgo, Javier; Hermann, Johannes Cornelius; Lemoine, Remy; Li, Hongju; Lovey, Allen John; Sjogren, Eric Brian; Soth, Michael
Patent: US2011/59118 A1, 2011 ;
Location in patent: Page/Page column 88-89 ;
反应条件
1: T=80°C; 2: With hydrogenchloride; water in tert-butyl alcohol T=80°C; 3: With water; sodium carbonate in ethyl acetate; tert-butyl alcohol
参考文献
PFIZER INC.
Patent: WO2009/16460 A2, 2009 ;
Location in patent: Page/Page column 80 ;
WO 2009/016460 A2
