3-溴-5-异丙氧基苯甲醛合成路线 （共 2 条）
反应条件
1: 1,3-dibromo-5-isopropoxy-benzene With n-butyllithium in diethyl ether T=-78°C; 0.5 h; Inert atmosphere; 2: N,N-dimethyl-formamide in diethyl ether T=-78 - -40°C; 1.5 h;
参考文献
AB SCIENCE; BENJAHAD, Abdellah; MOUSSY, Alain; CHEVENIER, Emmanuel; PICOUL, Willy; LERMET, Anne; PEZ, Didier; MARTIN, Jason; SANDRINELLI, Franck
Patent: WO2013/14170 A1, 2013 ;
Location in patent: Page/Page column 62; 63 ;
WO 2013/014170 A1
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C / |Inert atmosphere 1.2: 16 h / 0 - 20 °C 2.1: n-butyllithium / diethyl ether / 0.5 h / -78 °C / |Inert atmosphere 2.2: 1.5 h / -78 - -40 °C View Scheme
参考文献
AB SCIENCE; BENJAHAD, Abdellah; MOUSSY, Alain; CHEVENIER, Emmanuel; PICOUL, Willy; LERMET, Anne; PEZ, Didier; MARTIN, Jason; SANDRINELLI, Franck
Patent: WO2013/14170 A1, 2013 ;
WO 2013/014170 A1
