(S)-2-甲基琥珀酸-1-甲酯合成路线 （共 10 条）
反应条件
hydrogen; triethylamine; Ru2Cl4((R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)2 in tetrahydrofuran; toluene T=35°C; P=2206.5 Torr; 24 h; op = 79percent; Title compound not separated from byproducts;
参考文献
Kawano, Hiroyuki; Ishii, Youichi; Ikariya, Takao; Saburi, Masahiko; Yoshikawa, Sadao; et. al
Tetrahedron Letters, 1987 , vol. 28, # 17 p. 1905 - 1908
反应条件
hydrogen; [Rh(COD)(chiral phosphite ligand)2]BF4 in ethyl acetate T=20°C; P=825.066 Torr; 12 h;
参考文献
DEGUSSA AG
Patent: WO2006/45388 A1, 2006 ;
Location in patent: Page/Page column 21-22 ;
反应条件
modified cinchona alkaloid (DHQD)2AQN in diethyl ether T=25°C; 4 h; Title compound not separated from byproducts.;
参考文献
Chen; Deng
Journal of the American Chemical Society, 2001 , vol. 123, # 45 p. 11302 - 11303
反应条件
sodium hydroxide; porcine pancreatic lipase in water Ambient temperaturepH 7.2; Yield given. Yields of byproduct given;
参考文献
Salaun, J.; Karkour, B.; Ollivier, J.
Tetrahedron, 1989 , vol. 45, # 10 p. 3151 - 3162
反应条件
water; Candida cylindracea lipase 1.) 35 dg C, 7 d; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Gubie-Jampel, E.; Rousseau, G.
Tetrahedron Letters, 1987 , vol. 28, # 31 p. 3563 - 3564
反应条件
potassium permanganate; acetone
参考文献
Staellberg
Arkiv foer Kemi, 1958 , vol. 12, p. 79,81
反应条件
potassium dihydrogenphosphate; novozyme 435; K2HPO4 buffer in water pH=7.2; Product distribution; Further Variations:Reagentsdifferent enzyme;
参考文献
Ostermeier, Markus; Brunner, Bernhard; Korff, Christian; Helmchen, Guenter
European Journal of Organic Chemistry, 2003 , # 17 p. 3453 - 3459
反应条件
ueber das Chinin-Salz;
参考文献
Staellberg
Arkiv foer Kemi, 1958 , vol. 12, p. 79,81
反应条件
thionyl chloride 20 h; Heating;
参考文献
Salaun, J.; Karkour, B.; Ollivier, J.
Tetrahedron, 1989 , vol. 45, # 10 p. 3151 - 3162
反应条件
thionyl chloride 20 h; Heating;
参考文献
Salaun, J.; Karkour, B.; Ollivier, J.
Tetrahedron, 1989 , vol. 45, # 10 p. 3151 - 3162
