5,12-二氢吲哚并[3,2-a]咔唑合成路线 （共 9 条）
反应条件
in acetic acid
6 h; Heating;
参考文献
Janosik, Tomasz; Bergman, Jan
Tetrahedron, 1999 , vol. 55, # 8 p. 2371 - 2380
反应条件
hydrogenchloride; anhydrous sodium hydrogen carbonate; sulfuric acid; acetic acid; palladium/activated carbon in diethyl ether; ethyl acetate; toluene
参考文献
Kai, Takahiro; Komori, Masaki; Yamamoto, Toshihiro; Matsumoto, Megumi
Patent: US2011/315975 A1, 2011 ;
反应条件
1: hydrogenchloride / diethyl ether / 16 h / 20 °C / Inert atmosphere
2: palladium on activated charcoal / toluene / 3 h / 111 °C
3: acetic acid / 8 h / 118 °C / Inert atmosphere
View Scheme
参考文献
Nippon Steel Chemical Co., Ltd.
Patent: EP2415772 A1, 2012 ;
反应条件
1: palladium on activated charcoal / toluene / 3 h / 111 °C
2: acetic acid / 8 h / 118 °C / Inert atmosphere
View Scheme
参考文献
Nippon Steel Chemical Co., Ltd.
Patent: EP2415772 A1, 2012 ;
反应条件
palladium diacetate in acetic acid
Cyclization; 1 h; Heating;
参考文献
Chakrabarty; Batabyal; Khasnobis
Synthetic Communications, 2000 , vol. 30, # 20 p. 3651 - 3668
反应条件
1.1: 96 percent / pyridine / 20 °C
2.1: K2CO3; Cu-bronze / 25 h / Heating
2.2: 62 percent / aq. KOH / ethanol / 4.5 h / Heating
3.1: 16 percent / Pd(OAc)2 / acetic acid / 1 h / Heating
View Scheme
参考文献
Chakrabarty; Batabyal; Khasnobis
Synthetic Communications, 2000 , vol. 30, # 20 p. 3651 - 3668
反应条件
1.1: K2CO3; Cu-bronze / 25 h / Heating
1.2: 62 percent / aq. KOH / ethanol / 4.5 h / Heating
2.1: 16 percent / Pd(OAc)2 / acetic acid / 1 h / Heating
View Scheme
参考文献
Chakrabarty; Batabyal; Khasnobis
Synthetic Communications, 2000 , vol. 30, # 20 p. 3651 - 3668
反应条件
palladium on activated charcoal
参考文献
Tomlinson
Journal of the Chemical Society, 1951 , p. 809
Full Text Show Details
Hall; Plant
Journal of the Chemical Society, 1953 , p. 116,118
反应条件
1: 160 °C
2: palladium/charcoal
View Scheme
参考文献
Hall; Plant
Journal of the Chemical Society, 1953 , p. 116,118
