sodium hydroxide in methanol; water T=25°C; 30 h;

Multi-step reaction with 3 steps 1: 64 percent / 4-dimethylaminopyridine, pyridine / 0.5 h / Ambient temperature2: 99 percent / glucose / ethanol; dimethylsulfoxide / 4 h / 30 °C / bakers' yeast, pH=63: 70 percent / p-TsOH, CuSO4 / 24 h / 60 °C