FMOC-D-Alpha-苯基甘氨酸合成路线 （共 4 条）
反应条件
1: (DHQD)2AQN; 4 Angstroem molecular sieves / diethyl ether / 1 h / 23 °C 2: morpholine / Pd(PPh3)4 / tetrahydrofuran / 0.17 h / 23 °C View Scheme
参考文献
Organic Letters, , vol. 4, # 19 p. 3321 - 3324
反应条件
1: With 4-methyl-morpholine; chloroformic acid ethyl ester in tetrahydrofuran T=-10°C; 0.166667 h; 2: With sodium tetrahydroborate in tetrahydrofuran 3: With water in tetrahydrofuran
参考文献
Sureshbabu, Vommina V.; Naik, Shankar A.; Hemantha; Narendra; Das, Ushati; Guru Row, Tayur N.
Journal of Organic Chemistry, 2009 , vol. 74, # 15 p. 5260 - 5266
反应条件
1.1: TsCl; Py / tetrahydrofuran / 0.25 h / 0 °C 1.2: 92 percent / tetrahydrofuran; CH2Cl2 / 1 h / 0 °C 2.1: 84 percent / C6H5CO2Ag / dioxane; H2O / 6 h / 70 °C View Scheme
参考文献
Mueller, Annett; Vogt, Carla; Sewald, Norbert
Synthesis, 1998 , # 6 p. 837 - 841
反应条件
1: NEt3 / tetrahydrofuran / 0.25 h / -15 °C 2: tetrahydrofuran; diethyl ether / 3 h / Ambient temperature 3: silver benzoate, H2O / dioxane / Ambient temperature View Scheme
参考文献
Mueller, Annett; Vogt, Carla; Sewald, Norbert
Synthesis, 1998 , # 6 p. 837 - 841
