L-Selectridereg; in tetrahydrofuran 4 h; Heating;

in water T=20°C; Fischer indole synthesis;

1: [Cy5]-Naltrexone With hydroxymethylphenoxyethyl resin; triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; toluene T=20°C; 1 h; 2: N-phenylhydrazine monohydrochloride With 4 A molecular sieve; acetic acid in dichloromethane T=20°C; Fischer indole synthesis; 1 h; 3: With trifluoroacetic acid in dichloromethane T=20°C; 0.5 h;

1: With acetic acid in methanol; dichloromethane T=20°C; 1 h; 2: With trifluoroacetic acid in dichloromethane T=20°C; 0.5 h;

in water Fischer indole synthesis; 1.5 h; Reflux;

potassium carbonate in acetone 5 h; Heating;