N-甲基-纳曲吲哚,C-11合成路线 (共 4 条)
反应条件
hydrogen; triethylamine; palladium on activated charcoal in N,N-dimethyl-formamide P=258.6 Torr; 2 h; Ambient temperature;
参考文献
Lever, John R.; Johnson, Suzanne M.
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 2 p. 115 - 122
反应条件
hydrogen; ammonium formate; palladium on activated charcoal in methanol; N,N-dimethyl-formamide T=85°C; 0.166667 h;
参考文献
Lever, John R.; Kinter, Chris M.; Ravert, Hayden T.; Musachio, John L.; Mathews, William B.; Dannals, Robert F.
Journal of Labelled Compounds and Radiopharmaceuticals, 1995 , vol. 36, # 2 p. 137 - 146
反应条件
1: 21 percent / conc. HCl, glacial acetic acid / 1 h / Heating 2: 96 percent / H2, Et3N / 5percent Pd/C / dimethylformamide / 2 h / 258.6 Torr / Ambient temperature View Scheme
参考文献
Lever, John R.; Johnson, Suzanne M.
Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 2 p. 115 - 122
反应条件
acetic acid Heatingfurther reagent;
参考文献
Portoghese; Sultana; Nagase; Takemori
Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 281 - 282