1: bis(trichloromethyl) carbonate; Dimethylcarbaminsaeure-3-aminophenylester in tetrahydrofuran T=0 - 20°C; 0.5 h; 2: (S)-5-methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine in tetrahydrofuran 1 h; 3: With sodium hydrogencarbonate in tetrahydrofuran; methanol; water; ethyl acetate

in tetrahydrofuran 1 h; Inert atmosphere;