N-甲基-N-甲氧基胺盐酸盐合成路线 (共 166 条)
参考文献
Drew, Michael G. B.; Gorsuch, Stephen; Mann, John; Yoshida, Shimon
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 10 p. 1627 - 1636
反应条件
benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide
参考文献
Suto, Mark J.; Sullivan, Robert W.; Ransone, Lynn J.
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 24 p. 2925 - 2930
反应条件
pyridine in dichloromethane T=0 - 20°C; 3 h; Inert atmosphere;
参考文献
Trabbic, Christopher J.; Dietsch, Heather M.; Alexander, Evan M.; Nagy, Peter I.; Robinson, Michael W.; Overmeyer, Jean H.; Maltese, William A.; Erhardt, Paul W.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 1 p. 73 - 77
反应条件
4-methyl-morpholine; isobutyl chloroformate -25 deg C bis RT;
参考文献
Bold, Guido; Allmendinger, Thomas; Herold, Peter; Moesch, Luzia; Schaer, Hans-Peter; et al.
Helvetica Chimica Acta, 1992 , vol. 75, # 3 p. 865 - 882
反应条件
isobutyl chloroformate
参考文献
Statnick, Michael A.; Suter, Todd M.; Gackenheimer, Susan L.; Emmerson, Paul J.; Quimby, Steve J.; Gehlert, Donald R.; Wheeler, William J.; Mitch, Charles H.
European Journal of Pharmacology, 2003 , vol. 482, # 1-3 p. 139 - 150
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in dichloromethane T=20°C; Inert atmosphere;
参考文献
Yun, Jeong In; Kim, Hyoung Rae; Kim, Sang Kyum; Kim, Deukjoon; Lee, Jongkook
Tetrahedron, 2012 , vol. 68, # 4 p. 1177 - 1184
反应条件
1,1'-carbonyldiimidazole Inert atmosphere;
参考文献
Journal of the American Chemical Society, , vol. 135, # 2 p. 582 - 585
反应条件
sodium hydroxide in N,N-dimethyl-formamide
distillation;
参考文献
Gilbreath; Harris
Journal of the American Chemical Society, 1988 , vol. 110, # 18 p. 6172 - 6179
参考文献
Mitsui Chemicals, Inc.
Patent: US5932759 A1, 1999 ;
反应条件
perchloric acid; ammonium sulphamate; sodium isothiocyanate
T=50°C; Rate constant;
参考文献
Singer, Sandra S.; Singer, George M.; Cole, Barbara B.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4931 - 4935