N-甲基-N-甲氧基胺盐酸盐合成路线 （共 166 条）
反应条件
in dichloromethane T=0 - 20°C; 6.25 h;
参考文献
White, Jonathan M.; Tunoori, Ashok Rao; Turunen, Brandon J.; Georg, Gunda I.
Journal of Organic Chemistry, 2004 , vol. 69, # 7 p. 2573 - 2576
反应条件
in dichloromethane T=-25 - 20°C; 3 h; Yield given;
参考文献
Lucet, Denis; Le Gall, Thierry; Mioskowski, Charles; Ploux, Olivier; Marquet, Andree
Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 985 - 988
参考文献
Groesbeek, M.; Rood, G. A.; Lugtenburg, J.
Recueil des Travaux Chimiques des Pays-Bas, 1992 , vol. 111, # 3 p. 149 - 154
反应条件
triethylamine in dichloromethane
参考文献
Rhone-Poulenc Rorer Limited
Patent: US6211234 B1, 2001 ;
反应条件
in tetrahydrofuran T=-78°C;
参考文献
Murphy, John A.; Commeureuc, Aurelien G. J.; Snaddon, Thomas N.; McGuire, Thomas M.; Khan, Tanweer A.; Hisler, Kevin; Dewis, Mark L.; Carling, Robert
Organic Letters, 2005 , vol. 7, # 7 p. 1427 - 1429
反应条件
pyridine; hydrogenchloride; sodium carbonate in thionyl chloride; dichloromethane
参考文献
Akzo Nobel, N.V.
Patent: US6080773 A1, 2000 ;
反应条件
triethylamine in dichloromethane
参考文献
Faghih, Ramin; Dwight, Wesley; Gentles, Robert; Phelan, Kathleen; Esbenshade, Timothy A; Ireland, Lynne; Miller, Thomas R; Kang, Chae-Hee; Fox, Gerard B; Gopalakrishnan, Sujatha M; Hancock, Arthur A; Bennani, Youssef L
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 15 p. 2031 - 2034
反应条件
triethylamine; 1,1'-carbonyldiimidazole
参考文献
Lee, Ki-Ho; Park, Chun-Eung; Min, Kyung-Hyun; Shin, Yong-Je; Chung, Coo-Min; Kim, Hui-Ho; Yoon, Hae-Jeoung; Won-Kim; Ryu, Eun-Ju; Shin, Yu-Jin; Nam, Hyun-Sik; Cho, Jeong-Woo; Lee, Hee-Yoon
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5567 - 5571
反应条件
N-ethyl-N,N-diisopropylamine in ethyl acetate T=45°C; 1 h;
参考文献
GENENTECH, INC.
Patent: WO2009/155565 A1, 2009 ;
Location in patent: Page/Page column 98-99 ;
WO 2009/155565 A1
反应条件
triethylamine; 1,1'-carbonyldiimidazole
参考文献
Lee, Ki-Ho; Park, Chun-Eung; Min, Kyung-Hyun; Shin, Yong-Je; Chung, Coo-Min; Kim, Hui-Ho; Yoon, Hae-Jeoung; Won-Kim; Ryu, Eun-Ju; Shin, Yu-Jin; Nam, Hyun-Sik; Cho, Jeong-Woo; Lee, Hee-Yoon
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5567 - 5571
