1-(4-甲基苯甲酰基)哌嗪合成路线 （共 8 条）
反应条件
1: 4-methyl-benzoic acid With N-bromosuccinmide; triphenylphosphine in dichloromethane T=0 - 5°C; 0.25 h; 2: piperazine With pyridine in dichloromethane T=20°C; 0.666667 h;
参考文献
Bandgar; Bettigeri
Synthetic Communications, 2004 , vol. 34, # 16 p. 2917 - 2924
反应条件
1: Et3N / CH2Cl2 / 20 °C 2: CH2Cl2; ethanol / 20 °C View Scheme
参考文献
Synthesis, , # 3 p. 361 - 363
反应条件
in ethanol; dichloromethane T=20°C;
参考文献
Synthesis, , # 3 p. 361 - 363
反应条件
hydrogenchloride in dimethyl sulfoxide; acetonitrile T=25°C; Substitution; Kinetics;
参考文献
Journal of Organic Chemistry, , vol. 65, # 18 p. 5659 - 5663
反应条件
potassium chloride in ethanol; water T=25°C; pH=9.41; Kinetics; Further Variations:pH-values;
参考文献
Journal of Organic Chemistry, , vol. 70, # 19 p. 7788 - 7791
反应条件
potassium chloride in ethanol; water T=25°C; pH=5.37; Kinetics; Further Variations:pH-values;
参考文献
Journal of Organic Chemistry, , vol. 70, # 19 p. 7788 - 7791
反应条件
water in dimethyl sulfoxide T=25°C; aminolysis; Kinetics;
参考文献
Canadian Journal of Chemistry, , vol. 77, # 5-6 p. 659 - 666
反应条件
in ethanol; water T=25°C; pH=9.41; ionic strength 0.2 mol/L; Kinetics; Further Variations:pH-values;
参考文献
Journal of Physical Organic Chemistry, , vol. 19, # 8-9 p. 555 - 561
