6-甲基-3-吡啶 三氟甲烷磺酸合成路线 （共 19 条）
反应条件
pyridine in dichloromethane T=0°C; 1.5 h;
参考文献
WYETH; CURIS, INC.
Patent: WO2008/57469 A1, 2008 ;
Location in patent: Page/Page column 238-239 ;
反应条件
1: With pyridine in dichloromethane T=0°C; 1.5 h; 2: With sodium hydrogencarbonate in dichloromethane; water
参考文献
SHIONOGI and CO., LTD.
Patent: EP1422218 A1, 2004 ;
Location in patent: Page 157; 158; 225 ;
反应条件
triethylamine in dichloromethane 18 h; Ambient temperature;
参考文献
Tilley, Jefferson W.; Zawoiski, Sonja
Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 386 - 390
反应条件
trifluoromethanesulfonic acid anhydride; triethylamine in tetrahydrofuran
参考文献
Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Ridgill, Mark Peter; Shaw, Duncan Edward
Patent: US2001/39286 A1, 2001 ;
反应条件
trifluoromethanesulfonic acid anhydride in dichloromethane
反应条件
trifluoromethanesulfonic acid anhydride in dichloromethane
反应条件
in sodium hydroxide; dichloromethane; triethylamine
参考文献
US4788206 A1, ;
US4786646 A1, ;
US4927838 A1, ;
参考文献
US5314900 A1, ;
US 5314900 A
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethanol; water; toluene Heating / reflux;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1228067 B1, 2004 ;
Location in patent: Page 68 ;
反应条件
ethanol; water; potassium carbonate; tetrakis(triphenylphosphine) palladium(0) in toluene T=120°C; 16 h; In pressure tube;
参考文献
EP1036072 B1, ;
Page 80 ;
