in acetic acid 48 h; Ambient temperature;

Multi-step reaction with 5 steps 1: 1.) Mg / 1.) Et2O, 2.) reflux, 1 h2: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating3: 85percent hydrazine hydrate / butan-1-ol / Heating4: O2, CuCl / pyridine5: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C  

Multi-step reaction with 3 steps 1: 85percent hydrazine hydrate / butan-1-ol / Heating2: O2, CuCl / pyridine3: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C  

Multi-step reaction with 4 steps 1: (AcO)2Cu / acetic acid; H2O / 0.67 h / Heating2: 85percent hydrazine hydrate / butan-1-ol / Heating3: O2, CuCl / pyridine4: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C  

Multi-step reaction with 2 steps 1: O2, CuCl / pyridine2: LiAlH4 / bis-(2-methoxy-ethyl) ether / 15 °C