1-乙基-1H-咪唑-2-甲醛合成路线 （共 8 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide
参考文献
Seto, Masaki; Miyamoto, Naoki; Aikawa, Katsuji; Aramaki, Yoshio; Kanzaki, Naoyuki; Iizawa, Yuji; Baba, Masanori; Shiraishi, Mitsuru
Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 2 p. 363 - 386
反应条件
potassium carbonate in N,N-dimethyl-formamide T=50°C; 5 h;
参考文献
BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; CHU, Daniel
Patent: WO2011/130661 A1, 2011 ;
Location in patent: Page/Page column 133-134 ;
反应条件
hydrogen; nickel in ethanol T=50 - 55°C; Hydrogenation; P=22800 Torr; 24 h;
参考文献
Balkalova; Domnina; Chipanina; Afonin; Shulunova
Russian Chemical Bulletin, 1999 , vol. 48, # 5 p. 962 - 966
反应条件
n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide
反应条件
1: 1H-imidazole With potassium hydroxide in acetone 2 h; 2: ethyl bromide in acetone
参考文献
Kleyi, Phumelele; Walmsley, Ryan S.; Gundhla, Isaac Z.; Walmsley, Tara A.; Jauka, Tembisa I.; Dames, Joanna; Walker, Roderick B.; Torto, Nelson; Tshentu, Zenixole R.
South African Journal of Chemistry, 2012 , vol. 65, p. 231 - 238
反应条件
potassium carbonate in N,N-dimethyl-formamide T=50°C;
参考文献
Journal of Biological Chemistry, , vol. 286, # 22 p. 19422 - 19430
反应条件
sodium tetrahydroborate in methanol T=0°C; 0.666667 h;
参考文献
Tasaka; Teranishi; Matsushita; Tamura; Hayashi; Okonogi; Itoh
Chemical and Pharmaceutical Bulletin, 1994 , vol. 42, # 1 p. 85 - 94
反应条件
dihydrogen peroxide in water
参考文献
Kleyi, Phumelele; Walmsley, Ryan S.; Gundhla, Isaac Z.; Walmsley, Tara A.; Jauka, Tembisa I.; Dames, Joanna; Walker, Roderick B.; Torto, Nelson; Tshentu, Zenixole R.
South African Journal of Chemistry, 2012 , vol. 65, p. 231 - 238
