1.1: LiCl; lithium diisopropylamide / heptane; ethylbenzene; tetrahydrofuran / 1.5 h / -78 - 25 °C
1.2: 88 percent / heptane; ethylbenzene; tetrahydrofuran / 24 h / 0 °C
2.1: 95 percent / pyrrolidine; BH3-THF; n-butyllithium / tetrahydrofuran; hexane / 6 h / 25 °C
View Scheme
参考文献
Borzilleri; Zheng; Schmidt; Johnson; Kim; DiMarco; Fairchild; Gougoutas; Lee; Long; Vite
Journal of the American Chemical Society, 2000 , vol. 122, # 37 p. 8890 - 8897
1.1: 77 percent / dimethylformamide / 6 h / 120 °C
2.1: 90 percent / 4-methylmorpholine N-oxide; OsO4 / tetrahydrofuran; H2O / 3 h / 20 °C
3.1: H2NNH2*H2O / methanol / 1 h / Heating
3.2: 75 percent / HCl / H2O / 20 °C / pH 4
View Scheme
参考文献
Wang, Mingyao; McIntee, Edward J.; Shi, Yongli; Cheng, Guang; Upadhyaya, Pramod; Villalta, Peter W.; Hecht, Stephen S.
Chemical Research in Toxicology, 2001 , vol. 14, # 10 p. 1428 - 1434
