(R)-2-(4-氯苯甲酰胺基)-3-(1,2-二氢-2-氧代-4-喹啉基)丙酸合成路线 （共 3 条）
反应条件
potassium carbonate in water; acetone 2 h;
参考文献
Otsubo; Morita; Uchida; Yamasaki; Kanbe; Shimizu
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2906 - 2909
反应条件
2: 0.25 N HCl / Ambient temperature 3: 1.) 6 N HCl 2.) propylene oxide / 1.) reflux, 6 h 2.) EtOH, reflux, 15 min 4: 29 percent / K2CO3 / acetone; H2O / 2 h View Scheme
参考文献
Otsubo; Morita; Uchida; Yamasaki; Kanbe; Shimizu
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2906 - 2909
反应条件
1: 1.) 6 N HCl 2.) propylene oxide / 1.) reflux, 5 h 2.) EtOH, reflux, 30 min 2: 29 percent / K2CO3 / acetone; H2O / 2 h View Scheme
参考文献
Otsubo; Morita; Uchida; Yamasaki; Kanbe; Shimizu
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2906 - 2909
