2-氯-5H-吡咯并[3,2-d]嘧啶合成路线 （共 3 条）
反应条件
hydrogen; sodium hydrogencarbonate; palladium 10 on activated carbon in ethanol T=20°C; 3 h;
参考文献
CYTOPIA RESEARCH PTY LTD
Patent: WO2009/62258 A1, 2009 ;
Location in patent: Page/Page column 99 ;
WO 2009/062258 A1
反应条件
acetic acid T=140°C; 4 h;
参考文献
GLAXOSMITHKLINE LLC; QIN, Donghui; CHEUNG, Mui; JOSHI, Hemant; TANGIRALA, Raghuram; BETHI, Sridhar, Reddy
Patent: WO2012/162129 A1, 2012 ;
Location in patent: Page/Page column 103 ;
WO 2012/162129 A1
反应条件
iodine; sodium hydrogencarbonate; potassium iodide in water T=20°C; 1 h;
参考文献
CYTOPIA RESEARCH PTY LTD
Patent: WO2009/62258 A1, 2009 ;
Location in patent: Page/Page column 99 ;
WO 2009/062258 A1
