1: With di-isopropyl azodicarboxylate; triphenylphosphine
Gabriel synthesis; Inert atmosphere;
2: With hydrazine hydrate
Gabriel synthesis; Inert atmosphere;
3: With hydrogenchloride in water
Inert atmosphere;
参考文献
Tuchscherer, Andre; Schaarschmidt, Dieter; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich
European Journal of Inorganic Chemistry, 2011 , # 28 p. 4421 - 4428
1: 47.4 g / NaH / paraffin; tetrahydrofuran / 1.) room temperature, 1.5 h, 2.) reflux, 24 h
2: 58 percent / conc. HCl, MeOH / CH2Cl2 / 3 h / Heating
3: 92 percent / triethylbenzylammonium chloride, 30percent aq. NaOH / CH2Cl2 / 3 h / Ambient temperature
View Scheme
参考文献
Kocian, Oldrich; Chiu, Kwok W.; Demeure, Roger; Gallez, Bernard; Jones, Christopher J.; Thornback, John R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 5 p. 527 - 536
di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=0 - 20°C; Mitsunobu reaction;
参考文献
Jones, Ticora V.; Slutsky, Morris M.; Laos, Roberta; De Greef, Tom F. A.; Tew, Gregory N.
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17235 - 17240
Jones, Ticora V.; Slutsky, Morris M.; Laos, Roberta; De Greef, Tom F. A.; Tew, Gregory N.
Journal of the American Chemical Society, 2005 , vol. 127, # 49 p. 17235 - 17240
1: With di-isopropyl azodicarboxylate; triphenylphosphine in tetrahydrofuran
T=20°C; Gabriel synthesis; 12.5 h; Inert atmosphere;
2: With hydrazine hydrate in ethanol
Gabriel synthesis; Inert atmosphereReflux;
3: With hydrogenchloride in water
Inert atmosphere;
参考文献
Tuchscherer, Andre; Schaarschmidt, Dieter; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich
European Journal of Inorganic Chemistry, 2011 , # 28 p. 4421 - 4428
