1: 4-(N,N-dimethlyamino)pyridine; trichloromonobromomethane; Fonderma / 4 h / Reflux
2: N,N-dimethyl-formamide / 2 h / Reflux
3: hydrogenchloride; water / 12 h / Reflux
View Scheme
参考文献
Ho, Jonathan Z.; Wallace, Michael A.; Tang, Yui S.; Zhang, Andy S.; Braun, Matthew P.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 5-6 p. 251 - 253
pyridine in hexane
30 min below 30 deg C then 4.5 h;
参考文献
Bhati, Asharam; Hamilton, Richard J.; Steven, David A.; Aneja, Rajender; Padley, Frederick B.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 10 p. 1553 - 1558