2-甲基-2-环己烯-1-酮合成路线 （共 131 条）
反应条件
copper(I) bromide dimethylsulfide complex; boron trifluoride diethyl etherate in tetrahydrofuran
T=-78°C; 3 h;
参考文献
Piers, Edward; Yeung, Bik Wah Anissa; Fleming, Fraser F.
Canadian Journal of Chemistry, 1993 , vol. 71, # 3 p. 280 - 286
反应条件
tributylphosphine; copper(I) bromide dimethylsulfide complex
1)THF, -78 deg C, 20 min 2)-78 deg C, 1h, then -40 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Piers, Edward; Yeung, Bik Wah Anissa; Fleming, Fraser F.
Canadian Journal of Chemistry, 1993 , vol. 71, # 3 p. 280 - 286
反应条件
1: methylmagnesium bromide With N,N,N',N',N'',N''-hexamethylphosphoric triamide; copper(I) bromide dimethylsulfide complex in tetrahydrofuran
T=-40°C; 0.5 h; Inert atmosphere;
2: chloro-trimethyl-silane; 2-methylcyclohex-2-en-1-one in tetrahydrofuran
T=-40°C; 1 h; Inert atmosphere;
3: With triethylamine in tetrahydrofuran
Inert atmosphere;
参考文献
Heng, Rama; Zard, Samir Z.
Chemical Communications, 2011 , vol. 47, # 11 p. 3296 - 3298
参考文献
Huang; Forsyth
Journal of Organic Chemistry, 1995 , vol. 60, # 18 p. 5746 - 5747
反应条件
3β,17β-dihydroxy-17α-methylandrost-5-ene in diethyl ether; hexane; toluene
T=-78°C;
参考文献
Maruoka, Keiji; Nonoshita, Katsumasa; Yamamoto, Hisashi
Tetrahedron Letters, 1987 , vol. 28, # 46 p. 5723 - 5726
反应条件
3β,17β-dihydroxy-17α-methylandrost-5-ene in diethyl ether; hexane; toluene
T=-78°C;
参考文献
Maruoka, Keiji; Nonoshita, Katsumasa; Yamamoto, Hisashi
Tetrahedron Letters, 1987 , vol. 28, # 46 p. 5723 - 5726
参考文献
Birch
Journal of the Chemical Society, 1946 , p. 593,597
Journal of the Chemical Society, 1947 , p. 1642,1644, 1648
Full Text Show Details
Butz; Davies; Gaddis
Journal of Organic Chemistry, 1947 , vol. 12, p. 122,127
反应条件
1: 68 percent / toluene / 4 h / Heating
2: 71 percent / tetrahydrofuran; diethyl ether
3: PCC; SiO2 / CH2Cl2 / 1 h / 20 °C
View Scheme
参考文献
Kim, Hee Jin; Koo, Sangho
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 19 p. 3479 - 3481
反应条件
Ph(Bt); aluminium trichloride in methanol
T=80°C; 24 h;
参考文献
Chikashita, Hidenori; Miyazaki, Makoto; Itoh, Kazuyoshi
Synthesis, 1984 , # 4 p. 308 - 310
反应条件
trimethylsilyl bromide; ytterbium in tetrahydrofuran
8 h; Heating;
参考文献
Taniguchi, Yuki; Nakahashi, Manabu; Kuno, Tatsuhiro; Tsuno, Masumi; Makioka, Yoshikazu; Takaki, Ken; Fujiwara, Yuzo
Tetrahedron Letters, 1994 , vol. 35, # 24 p. 4111 - 4114
