7-溴双环[4.1.0]庚烷合成路线 （共 22 条）
反应条件
1: in tetrahydrofuran
T=20°C; 0.5 h;
2: With water in tetrahydrofuran
T=20°C; Further byproducts given. Title compound not separated from byproducts;
参考文献
Baird, Mark S; Nizovtsev, Alexey V; Bolesov, Ivan G
Tetrahedron, 2002 , vol. 58, # 8 p. 1581 - 1593
反应条件
1: 57 percent / O2
2: MgCl2, K / tetrahydrofuran / 8 h / -50 - -40 °C
View Scheme
参考文献
Ando, Teiichi; Muranaka, Takeshi; Ishihara, Takashi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3227 - 3228
反应条件
1: n-BuLi / tetrahydrofuran / 0.08 h / -95 °C
2: 2.) MeOH / 1.) -50 deg C, THF, 30 min; 2.) -95 deg C
View Scheme
参考文献
Warner, Philip M.; Chang, Suae-Chen; Koszewski, Nicholas J.
Tetrahedron Letters, 1985 , vol. 26, # 44 p. 5371 - 5374
反应条件
in ammonia
Irradiationor in MeOH as solvent;
参考文献
Meijs, Gordon F.
Journal of Organic Chemistry, 1984 , vol. 49, # 20 p. 3863 - 3865
反应条件
magnesium chloride
T=-50 - -40°C; 8 h; Yield given. Yields of byproduct given;
参考文献
Ando, Teiichi; Muranaka, Takeshi; Ishihara, Takashi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3227 - 3228
反应条件
magnesium chloride
T=-50 - -40°C; 8 h; Yield given. Yields of byproduct given;
参考文献
Ando, Teiichi; Muranaka, Takeshi; Ishihara, Takashi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3227 - 3228
反应条件
magnesium chloride
T=-50 - -40°C; 8 h; Yield given. Yields of byproduct given;
参考文献
Ando, Teiichi; Muranaka, Takeshi; Ishihara, Takashi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 3227 - 3228
反应条件
methanol
1.) -50 deg C, THF, 30 min; 2.) -95 deg C; Multistep reaction. Title compound not separated from byproducts;
参考文献
Warner, Philip M.; Chang, Suae-Chen; Koszewski, Nicholas J.
Tetrahedron Letters, 1985 , vol. 26, # 44 p. 5371 - 5374
反应条件
1.) THF, -80 to -50 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Scott, Frederick; Mafunda, Brownlee G; Normant, Jean F.; Alexakis, Alexandre
Tetrahedron Letters, 1983 , vol. 24, # 51 p. 5767 - 5770
反应条件
(t-BuO)2 in benzene
Heating;
参考文献
Akhmetkhanova, F. M.; Rol'nik, L. Z.; Proskurnina, M. V.; Zlot-skii, S. S.; Rakhmankulov, D. L.
J. Gen. Chem. USSR (Engl. Transl.), 1989 , vol. 59, # 31 p. 567 - 571,502 - 504
