1: 88 percent / DCC, DMAP / CHCl3 / 12.2 h / 0 - 20 °C 2: 84 percent / H2, 0.1 N aq. HCl / 10percent Pd/C / methanol / 7.5 h / 760 Torr View Scheme

With  ammonia; hydrogen; nickel in  methanol; water P=2585.7 Torr; 2.5 h;   

Multi-step reaction with 3 steps 1: 98 percent / pyridine / 1.5 h / 100 °C2: 98 percent / DCC, DMAP / CHCl3 / 24.5 h / 0 - 20 °C3: 82 percent / H2, NH3 / Raney Ni / methanol; H2O / 2.5 h / 2585.7 Torr  

Multi-step reaction with 2 steps 1: 98 percent / DCC, DMAP / CHCl3 / 24.5 h / 0 - 20 °C2: 82 percent / H2, NH3 / Raney Ni / methanol; H2O / 2.5 h / 2585.7 Torr  

Multi-step reaction with 3 steps 1: 88 percent / H2, NH3 / Raney Ni / methanol; H2O / 3 h / 2585.7 Torr2: 98 percent / DCC, DMAP / CHCl3 / 24.5 h / 0 - 20 °C3: 82 percent / H2, NH3 / Raney Ni / methanol; H2O / 2.5 h / 2585.7 Torr  

With  4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in  chloroform T=0 - 20°C; 12.2 h;