N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride in N,N,N',N',N'',N''-hexamethylphosphoric triamide; water; dimethyl sulfoxide T=175°C;

With  diazomethane; potassium permanganate; sodium periodate; sodium carbonate in  1,4-dioxane; diethyl ether; water  

Multi-step reaction with 3 steps 1: 87 percent / LiAlH4 / tetrahydrofuran / -78 - 20 °C2: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 3: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether  

Multi-step reaction with 5 steps 1: dicyclohexylcarbodiimide, hydroxybenzotriazole / 1.) THF 2.) Et3N2: 57 percent / lithium diisopropylamine / tetrahydrofuran; hexamethylphosphoric acid triamide / -55 °C3: 87 percent / LiAlH4 / tetrahydrofuran / -78 - 20 °C4: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 5: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether  

Multi-step reaction with 4 steps 1: 57 percent / lithium diisopropylamine / tetrahydrofuran; hexamethylphosphoric acid triamide / -55 °C2: 87 percent / LiAlH4 / tetrahydrofuran / -78 - 20 °C3: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 4: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether  

Multi-step reaction with 2 steps 1: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 2: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether  

Multi-step reaction with 6 steps 1: 94 percent / methanol; tetrahydrofuran / -60 - 10 °C2: dicyclohexylcarbodiimide, hydroxybenzotriazole / 1.) THF 2.) Et3N3: 57 percent / lithium diisopropylamine / tetrahydrofuran; hexamethylphosphoric acid triamide / -55 °C4: 87 percent / LiAlH4 / tetrahydrofuran / -78 - 20 °C5: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 6: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether