[3aS-(3aa,4a,5b,6aa)]-4-[[[(叔丁基)二甲基硅]氧]甲基]-5-[(四氢-2H-吡喃-2-基)氧基]六氢-2(1H)-二并环戊二烯酮合成路线 (共 11 条)
反应条件
1: 94 percent / methanol; tetrahydrofuran / -78 °C 2: 57 percent / lithium diisopropylamine / tetrahydrofuran; hexamethylphosphoric acid triamide / -55 °C 3: 87 percent / LiAlH4 / tetrahydrofuran / -78 - 20 °C 4: imidazole, pyridinum toluene-p-sulphonate / 1.) dimethylformamide 2.) Ch2Cl2 5: 84 percent / NaIO4, KMnO4, Na2CO3, CH2N2 / dioxane; H2O; diethyl ether 6: 81 percent / NaH, hexamethylphosphoramide / dimethylsulfoxide; hexamethylphosphoric acid triamide; H2O / 175 °C View Scheme
参考文献
Journal of the Chemical Society - Series Chemical Communications, , vol. No. 4, p. 267 - 268