1: ammonium acetate; ammonia / ethanol; water / 4 h / 20 °C / Large scale reaction
2: sodium ethanolate / butan-1-ol / 12 h / 80 °C / Large scale reaction
View Scheme
参考文献
Graham, Jonathan P.; Langlade, Nathalie; Northall, John M.; Roberts, Alastair J.; Whitehead, Andrew J.
Organic Process Research and Development, 2011 , vol. 15, # 1 p. 44 - 48
1: 3-amino-5,5-dimethyl-2-cyclohexen-1-one; 4-bromo-benzaldehyde With toluene-4-sulfonic acid in water
T=150°C; 0.0333333 h; microwave irradiation;
2: 1H-indene-1,3(2H)-dione in water
T=150°C; 0.05 h; microwave irradiation; Further stages.;
