1: trimethylaluminum With 1,4-diaza-bicyclo[2.2.2]octane in toluene T=0°C; 2: 4-bromo-benzaldehyde With [(R)-1,1'-binaphthyl-2,2'-diyldioxy]{bis[(S)-(1-phenylethyl)]amino}phosphine; bis(acetylacetonate)nickel(II) in tetrahydrofuran T=5°C; 1 h; Title compound not separated from byproducts;
参考文献
Mata, Yvette; Dieguez, Montserrat; Pamies, Oscar; Woodward, Simon
Journal of Organic Chemistry, 2006 , vol. 71, # 21 p. 8159 - 8165
1: dimethyl zinc With (2S)-1-(ferrocenylmethyl)aziridin-2-yl(diphenyl)methanol in toluene T=0 - 40°C; Inert atmosphere; 2: 4-bromo-benzaldehyde in toluene T=0 - 30°C; 3: With water; ammonium chloride in toluene optical yield given as percent eeenantioselective reaction;
