1: H2, Rh(acac)(CO)2, (R)-2-Nap-BIPNITE-p-F / decane / 6 h / 60 °C / 38000 Torr 2: NaClO2, 30percent H2O2, Na2HPO4 / acetonitrile; H2O / 3 h / 10 °C View Scheme

Multi-step reaction with 4 steps 1: H2 / Pd/C-HCl / ethyl acetate2: pyridine / 0 °C3: sodium iodide / acetone / 12 h / Heating4: 24 percent / DBU / toluene / 100 °C  

Multi-step reaction with 5 steps 1: 85 percent / H2 / Pd/C-HCl / ethyl acetate2: 82 percent / pyridine / 0 °C3: 90 percent / sodium iodide / acetone / 12 h / Heating4: 91 percent / DBU / toluene / 100 °C5: 74 percent / cerium (IV) ammonium nitrate / acetonitrile / 1 h / -10 °C