1,4-二氮杂环庚烷-1-甲酸叔丁酯合成路线

参考文献

Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

287114-32-31-吡啶-1,4-二氮杂庚烷

参考文献

Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642

108-86-1溴代苯+

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

61903-27-31-苯基-1,4-二氮杂环庚烷

参考文献

Castelhano, Arlindo; McKibben, Bryan; Steinig, Arno
Patent: US2003/229067 A1, 2003 ;
Location in patent: Page 30 ;
US 20030229067 A1

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

61903-27-31-苯基-1,4-二氮杂环庚烷

参考文献

Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

152943-97-01-(2-甲氧基苯基)-[1,4]二氮杂烷

参考文献

Li, Aixiao; Mishra, Yogesh; Malik, Maninder; Wang, Qi; Li, Shihong; Taylor, Michelle; Reichert, David E.; Luedtke, Robert R.; MacH, Robert H.
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2988 - 2998

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

348134-09-86-氯-2-(1,4-氮杂-1-基)-1,3-苯并噻唑

参考文献

Zindell, Renee; Walker, Edward R.; Scott, John; Amouzegh, Patricia; Wu, Lifen; Ermann, Monika; Thomson, David; Fisher, Micheal B.; Fullenwider, Cody Lee; Grbic, Heather; Kaplita, Paul; Linehan, Brian; Patel, Mita; Patel, Monica; Loebbe, Sabine; Block, Svenja; Albrecht, Claudia; Gemkow, Mark J.; Shih, Daw-Tsun; Riether, Doris
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 14 p. 4276 - 4280

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

326860-05-3

参考文献

Saito, Keiji; Nakao, Akira; Shinozuka, Tsuyoshi; Shimada, Kousei; Matsui, Satoshi; Oizumi, Kiyoshi; Yano, Kazuki; Ohata, Keiko; Nakai, Daisuke; Nagai, Yoko; Naito, Satoru
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 7 p. 1628 - 1642

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

223796-20-1

参考文献

Nielsen, Simon Feldbk; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Liljefors, Tommy; Peters, Dan
Journal of Medicinal Chemistry, 2000 , vol. 43, # 11 p. 2217 - 2226

144100-07-2+

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

1152093-60-1

参考文献

F. HOFFMANN-LA ROCHE AG; GENENTECH, INC.; DO, Steven; HU, Huiyong; KOLESNIKOV, Aleksandr; TSUI, Vickie, H.; WANG, Xiaojing
Patent: WO2014/1377 A1, 2014 ;
Location in patent: Page/Page column 103 ;

112275-50-01,4-二氮杂环庚烷-1-甲酸叔丁酯

74418-15-8

参考文献

Foley, Timothy L.; Rai, Ganesha; Yasgar, Adam; Daniel, Thomas; Baker, Heather L.; Attene-Ramos, Matias; Kosa, Nicolas M.; Leister, William; Burkart, Michael D.; Jadhav, Ajit; Simeonov, Anton; Maloney, David J.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 1063 - 1078