3,5-二甲基-2-环己烯-1-酮合成路线 （共 86 条）
反应条件
1: sodium; alcohol
2: P2O5 / 140 °C
3: HNO3+H2SO4
View Scheme
参考文献
Knoevenagel
Justus Liebigs Annalen der Chemie, 1896 , vol. 289, p. 143
Justus Liebigs Annalen der Chemie, 1897 , vol. 297, p. 119,160, 175
反应条件
scandium tris(trifluoromethanesulfonate) in chlorobenzene
42 h; Reflux;
参考文献
Boe, Esther; Hillringhaus, Tim; Nitsch, Jacqueline; Klussmann, Martin
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 6 p. 1744 - 1748
反应条件
hydrogen; ethylmethylphenylphosphine; tert-butyl alcohol; [{(Ph3P)CuH}6] in benzene
T=20°C; Catalytic hydrogenation; P=25857.4 Torr; 20 h;
参考文献
Chen, Jian-Xin; Daeuble, John F.; Stryker, Jeffrey M.
Tetrahedron, 2000 , vol. 56, # 18 p. 2789 - 2798
反应条件
lithium n-butyldiisobutylaluminum hydride; (2,6-t-Bu2-4-Me-C6H2O)2AlMe in diethyl ether; hexane; toluene
T=-78°C; 0.25 h;
参考文献
Nonoshita, Katsumasa; Maruoka, Keiji; Yamamoto, Hisashi
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 2241 - 2243
反应条件
potassium tri-sec-butyl-borohydride
参考文献
Olah,G.A. et al.
Journal of the American Chemical Society, 1972 , vol. 94, p. 3544 - 3551
反应条件
sodium tetrahydroborate; SmCpCl2(THF)3 in methanol
6 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Komiya, Sanshiro; Tsutsumi, Osamu
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 9 p. 3423 - 3424
