3,5-二甲基-4-硝基异噁唑合成路线 （共 36 条）
反应条件
piperidine
T=20°C; Knoevenagel condensation; 0.166667 h;
参考文献
Rajanarendar; Ramesh; Karunakar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1994 - 1996
反应条件
[C4mim][OH]
T=20°C; Michael condensation; 0.5 h;
参考文献
Rajanarendar; Murthy, K. Rama; Shaik, Firoz Pasha; Reddy, M. Nagi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 4 p. 587 - 592
反应条件
piperidine in ethanol
T=150°C; 1 h;
参考文献
Kochetkov,N.K. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1962 , vol. 32, p. 1778 - 1785,1763 - 1769
反应条件
1: piperidine / ethanol / Heating
2: SnCl2, aq. HCl
View Scheme
参考文献
Rao,C.J.; Murthy,A.K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16, p. 636 - 637
反应条件
1: piperidine / ethanol / Heating
2: SnCl2, aq. HCl
View Scheme
参考文献
Rao,C.J.; Murthy,A.K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1978 , vol. 16, p. 636 - 637
反应条件
1: 85 percent / piperidine / ethanol / 1.5 h / Heating
2: 60 percent / Et3N / 3 h / Heating
3: 45 percent / tin(II) chloride, conc. HCl / 2 h
View Scheme
参考文献
Malla Reddi, Kooturu; Janakirama Rao, Citineni; Krishna Murthy, Ananthula
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 11 p. 3617 - 3618
反应条件
piperidine
T=20°C; Knoevenagel condensation; 0.166667 h;
参考文献
Rajanarendar; Ramesh; Karunakar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1994 - 1996
反应条件
1: piperidine / ethanol / 1 h / 60 °C
2: ethanol / 6 h / 60 °C
View Scheme
参考文献
Rajanarendar; Ramesh; Karunakar
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 8 p. 1994 - 1996
反应条件
1: piperidine / ethanol / 1 h / 80 °C
2: piperidine / ethanol / 2 h / 80 °C
View Scheme
参考文献
Rajanarendar; Nagi Reddy; Rama Murthy
Chinese Chemical Letters, 2010 , vol. 21, # 8 p. 927 - 930
反应条件
1: With piperidine in tetrahydrofuran
T=70 - 80°C; 12 h;
2: With potassium permanganate in tetrahydrofuran; water; acetone
T=20°C; Further stages.;
参考文献
Adamo, Mauro F.A.; Konda, Vivekananda R.; Donati, Donato; Sarti-Fantoni, Piero; Torroba, Tomas
Tetrahedron, 2007 , vol. 63, # 39 p. 9741 - 9745
