甲基(2E,4S)-(-)-4-(苯甲氧基)戊基-2-烯酸合成路线 （共 9 条）
反应条件
potassium hydride in tetrahydrofuran T=-78°C; 1 h;
参考文献
Annunziata, Rita; Cinquini, Mauro; Cozzi, Franco; Dondio, Gulio; Raimondi, Laura
Tetrahedron, 1987 , vol. 43, # 10 p. 2369 - 2380
反应条件
triethylamine; lithium bromide in acetonitrile T=0 - 20°C; 12 h;
参考文献
Enders, Dieter; Jandeleit, Bernd; Von Berg, Stefan
Journal of Organometallic Chemistry, 1997 , vol. 533, # 1-2 p. 219 - 236
反应条件
benzoic acid in toluene T=90°C; Wittig reaction; 0.166667 h; Title compound not separated from byproducts.;
参考文献
Organic letters, , vol. 3, # 22 p. 3591 - 3593
反应条件
sodium hydride in tetrahydrofuran T=-60°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 44, # 2 p. 491 - 502
反应条件
in methanol 2 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 43, # 8 p. 1895 - 1902
反应条件
1: 95 percent / TfOH / CH2Cl2; cyclohexane / 60 h / Ambient temperature 2: 98 percent / DIBAH / diethyl ether / 1 h / -78 °C 3: 86 percent / Et3N, LiBr / acetonitrile / 12 h / 0 - 20 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 533, # 1-2 p. 219 - 236
反应条件
1: 98 percent / DIBAH / diethyl ether / 1 h / -78 °C 2: 86 percent / Et3N, LiBr / acetonitrile / 12 h / 0 - 20 °C View Scheme
参考文献
Journal of Organometallic Chemistry, , vol. 533, # 1-2 p. 219 - 236
反应条件
1: diethoxyphosphoryl-acetic acid ethyl ester; (S)-2-(benzyloxy)-propionaldehyde With lithium chloride 2: acetonitrile With 1,8-diazabicyclo[5.4.0]undec-7-ene
参考文献
Organic Letters, , vol. 10, # 10 p. 2079 - 2081
反应条件
sodium hydride 1.) THF, -30 deg C, 30 min, 2.) THF, -30 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Asymmetry, , vol. 2, # 12 p. 1329 - 1342
