1-吡咯烷-1-环己烯合成路线 （共 146 条）
反应条件
1: 3-azido-2-cyclohexen-1-one; methyl(diphenyl)-phosphine in dichloromethane T=20°C; Substitution; Staudinger reaction; 0.5 h; 2: 4-nitrobenzaldehdye in chloroform T=45°C; Addition; aza-Wittig reaction; 3: 1-cyclohex-1-enylpyrrolidine in chloroform T=20°C; Cycloaddition; 17 h;
参考文献
Palacios, Francisco; Herran, Esther; Rubiales, Gloria
Journal of Organic Chemistry, 1999 , vol. 64, # 17 p. 6239 - 6246
反应条件
C18H32ClIrOP2S; sodium t-butanolate in para-xylene T=150°C; 24 h; Inert atmosphereSchlenk techniqueGloveboxSealed tube;
参考文献
Angewandte Chemie - International Edition, , vol. 53, # 5 p. 1390 - 1394
Angew. Chem., , vol. 126, # 5 p. 1414 - 1418
反应条件
C18H32ClIrOP2S; sodium t-butanolate in para-xylene T=150°C; 24 h; Inert atmosphereSchlenk techniqueGloveboxSealed tube;
参考文献
Angewandte Chemie - International Edition, , vol. 53, # 5 p. 1390 - 1394
Angew. Chem., , vol. 126, # 5 p. 1414 - 1418
反应条件
4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide T=0°C; 2 h;
参考文献
Tetrahedron Letters, , vol. 31, # 25 p. 3579 - 3582
反应条件
zinc in pyridine T=20°C; P=2250.2 - 3000.2 Torr; other enamines;
参考文献
Tordeux, Marc; Francese, Catherine; Wakselman, Claude
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 1951 - 1957
反应条件
(i) pentane, (ii) aq. H2SO4; Multistep reaction;
参考文献
Pezacki, John Paul; Couture, Philippe; Dunn, James A.; Warkentin, John; Wood, Paul D.; Lusztyk, Janusz; Ford, Francis; Platz, Matthew S.
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4456 - 4464
反应条件
1: pentane 2: H3O(1+) 3: 85 percent / tetrabutylammonium fluoride*3H2O / tetrahydrofuran View Scheme
参考文献
Rico, I.; Cantacuzene, D.; Wakselman, C.
Tetrahedron Letters, 1981 , vol. 22, # 35 p. 3405 - 3408
反应条件
hydrogenchloride; tetramethyl-ammonium fluoride 1) DMF, 70 deg C, 10 h, irradiated, 2) r.t., 3 h; Yield given. Multistep reaction;
参考文献
Chen, Qing-Yun; Li, Zhan-Ting
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 6 p. 645 - 648
反应条件
di-tert-butylnitroxide radical in N,N-dimethyl-formamide 0.333333 h; Irradiation;
参考文献
Russell, Glen A.; Wang, Keyang
Journal of Organic Chemistry, 1991 , vol. 56, # 11 p. 3475 - 3479
反应条件
in chloroform T=20 - 60°C; Diels-Alder reaction; 14 h; regioselective reaction;
参考文献
Anderson, Erin D.; Boger, Dale L.
Journal of the American Chemical Society, 2011 , vol. 133, # 31 p. 12285 - 12292
