8-羟基喹啉-N-氧化物合成路线 （共 25 条）
反应条件
1: HCl 2: KOH / H2O 3: K2CO3; KI / methanol 4: H(1+) 5: LiAlBH4 / tetrahydrofuran 6: pyridine 7: KOtBu / 2-methyl-propan-2-ol View Scheme
参考文献
Deyrup; Nowicki; Richards; Otero; Harrison; Baker
Naunyn-Schmiedeberg's Archives of Pharmacology, 1999 , vol. 359, # 3 p. 168 - 177
反应条件
1: 95 percent / CCl4 / 10 h / Heating 2: 72 percent / H2O / 3 h / 0 °C 3: 70 percent / NaOH / H2O / 4 h / Heating View Scheme
参考文献
Shrader, William D.; Celebuski, Joseph; Kline, Steven J.; Johnson, David
Tetrahedron Letters, 1988 , vol. 29, # 12 p. 1351 - 1354
反应条件
3: 95 percent / potassium carbonate / acetone / 1 h 4: 60 percent / aq. NaOH / 4 h / Heating View Scheme
参考文献
Rao. A. V. Rama; Chavan, Subhash P.; Sivadasan, Latha
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 496 - 497
反应条件
1: CCl4
2: H2O
View Scheme
参考文献
Albrecht, Markus; Osetska, Olga; Froehlich, Roland
Synlett, 2006 , # 6 p. 924 - 926
反应条件
hydrogenchloride; nitric acid
参考文献
Shaikh; Johnson; Grollman
Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1329 - 1340
