反应条件
Multi-step reaction with 4 steps 1: PCl5 / 1,2-dichloro-ethane / 0.33 h / 23 °C2: AlCl3 / 1,2-dichloro-ethane3: 1.) LDA / 1.) THF, hexane, -78 deg C, 1.5 h, 2.) THF, hexane, -78 deg C, 1.5 h4: KOH / ethanol / 4 h / 23 °C
参考文献
Lipinski, Christopher A.; Aldinger, Charles E.; Beyer, Thomas A.; Bordner, Jon; Burdi, Douglas F.; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2169 - 2177
