4-(1H-1,2,4-三唑-1-基甲基)苯甲腈合成路线 （共 12 条）
反应条件
1: 4-fluorobenzenecarbonitrile With lithium hexamethyldisilazane in tetrahydrofuran T=-20°C; 0.0833333 h; 2: 4-(1-imidazolylmethyl)-benzonitrile in tetrahydrofuran T=-15°C; 0.5 h; Product distribution / selectivity;
参考文献
CIPLA LIMITED; CURTIS, Philip, Anthony
Patent: WO2007/107733 A1, 2007 ;
Location in patent: Page/Page column 13; 15; 17 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=-15°C; 3 h; Product distribution / selectivity;
参考文献
CADILA HEALTHCARE LIMITED
Patent: WO2007/54964 A2, 2007 ;
Location in patent: Page/Page column 5; 11 ;
