4-(4-氰基苄基)-1,2,4-噻唑合成路线 (共 4 条)
反应条件
potassium carbonate; potassium iodide in acetone T=55°C; 8 h; Product distribution / selectivity;
参考文献
WO2005/47269 A1, ;
Page/Page column 7-8 ;
反应条件
in N,N-dimethyl-formamide T=-10 - 5°C; 0.5 h; Product distribution / selectivity;
参考文献
US2007/66831 A1, ;
Page/Page column 6-7; 9 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=-15°C; 3 h; Product distribution / selectivity;
参考文献
CADILA HEALTHCARE LIMITED
Patent: WO2007/54964 A2, 2007 ;
Location in patent: Page/Page column 5; 11 ;
反应条件
potassium tert-butylate in tetrahydrofuran T=-15°C; 3 h; Product distribution / selectivity;
参考文献
CADILA HEALTHCARE LIMITED
Patent: WO2007/54964 A2, 2007 ;
Location in patent: Page/Page column 5; 11 ;