反应条件
Multi-step reaction with 9 steps 1: 42 percent / imidazole / dimethylformamide / 1.5 h / 20 °C2: 1.) ozone 2.) PPh3 / 1.) CH2Cl2, MeOH, -60 deg C 2.) CH2Cl2, MeOH, -60 to 0 deg C3: NaHCO3 / aq. ethanol / Heating5: N-methylmorpholine N-oxide, selenium dioxide6: imidazole / dimethylformamide7: 55 percent / NaBH4, CeCl3*6H2O / methanol / further reag.: (S)-BINAL-H8: anthracene, triethylamine / toluene / 1 h / 20 °C / Irradiation9: 72 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.83 h / 60 °C
参考文献
Calverley Tetrahedron, 1987 , vol. 43, # 20 p. 4609-4619