反应条件
1: 84 percent / 1.) Et3N / CH2Cl2 / 1.) 5 deg C, 1 h, 2.) 20 deg C, 1 h 2: 82 percent / activated Fe, FeSO4*7H2O / methanol; H2O / 5 h / 70 °C 3: 48 percent / 2,6-lutidine / dimethylformamide; toluene / 24 h / 70 °C 4: 22 percent / 2,6-lutidine / various solvent(s) / 18 h / 80 °C 5: 41 percent / 1 N aq. NaOH / 2 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 34, # 5 p. 1594 - 1605
